Browsing Experimentally Confirmed database

Result: Your query found 19 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
baeR
  • BacMet ID: BAC0039
  • Code for: Regulator
  • Family: Contains 1 response regulatory domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons. Overexpression of BaeR increases resistance to novobiocin and deoxycholate. BaeR upregulates the mdtABCD locus and acrD and thereby increases the resistance to deoxycholate, metals and antibiotics.
  • Length (amino acid): 240
  • Reference: Baranova et al. 2002; Pubmed- 12107134, Yamamoto et al. 2008; Pubmed- 17884222, Lee et al. 2005; Pubmed- 15659689, Leblanc et al 2011; Pubmed- 21515766

    		• Similar resistance genes in 'BacMet Predicted database'
    baeR
  • BacMet ID: BAC0596
  • Code for: Regulator
  • Family: Contains 1 response regulatory domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Salmonella Typhimurium
  • Location: Chromosome
  • Compound: Copper (Cu), Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 240
  • Reference: Nishino et al. 2007; Pubmed- 17933888, Appia-Ayme et al. 2011; Pubmed- 21886814

    		• Similar resistance genes in 'BacMet Predicted database'
    baeS
  • BacMet ID: BAC0040
  • Code for: Regulator
  • Family: Contains 1 HAMP domain, 1 histidine kinase domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 467
  • Reference: Baranova et al. 2002; Pubmed- 12107134, Yamamoto et al. 2008; Pubmed- 17884222, Lee et al. 2005; Pubmed- 15659689, Leblanc et al 2011; Pubmed- 21515766

    		• Similar resistance genes in 'BacMet Predicted database'
    baeS
  • BacMet ID: BAC0597
  • Code for: Regulator
  • Family: Contains 1 HAMP domain, 1 histidine kinase domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Salmonella Typhimurium
  • Location: Chromosome
  • Compound: Copper (Cu), Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 467
  • Reference: Nishino et al. 2007; Pubmed- 17933888, Appia-Ayme et al. 2011; Pubmed- 21886814

    		• Similar resistance genes in 'BacMet Predicted database'
    modA
  • BacMet ID: BAC0598
  • Code for: Binding protein
  • Family: ABC superfamily, bacterial solute-binding protein ModA family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdenum ABC transporter, periplasmic molybdenum-binding protein. Part of the ModABC transport system.
  • Length (amino acid): 269
  • Reference: Kazarov et al. 2013; Pubmed- 23913324

    		• Similar resistance genes in 'BacMet Predicted database'
    modA
  • BacMet ID: BAC0609
  • Code for: Binding protein
  • Family: ABC superfamily, bacterial solute-binding protein ModA family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdate-binding periplasmic protein. Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity.
  • Length (amino acid): 257
  • Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363

    		• Similar resistance genes in 'BacMet Predicted database'
    modB
  • BacMet ID: BAC0599
  • Code for: Enzyme
  • Family: ABC superfamily, binding-protein-dependent transport system permease family. CysTW subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdenum ABC transporter, permease protein. Part of the ModABC transport system. Responsible for the translocation of the substrate across the membrane. modB gene encodes the integral membrane protein ModB, which builds the membrane channel of the ModABC transporter.
  • Length (amino acid): 233
  • Reference: Kazarov et al. 2013; Pubmed- 23913324

    		• Similar resistance genes in 'BacMet Predicted database'
    modB
  • BacMet ID: BAC0610
  • Code for: Enzyme
  • Family: ABC superfamily, binding-protein-dependent transport system permease family. CysTW subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdenum transport system permease protein ModB. Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
  • Length (amino acid): 229
  • Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363

    		• Similar resistance genes in 'BacMet Predicted database'
    modC
  • BacMet ID: BAC0600
  • Code for: Enzyme
  • Family: ABC superfamily, Molybdate importer family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdenum ABC transporter, ATPase subunit of the ModABC complex. Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
  • Length (amino acid): 253
  • Reference: Kazarov et al. 2013; Pubmed- 23913324

    		• Similar resistance genes in 'BacMet Predicted database'
    modC
  • BacMet ID: BAC0611
  • Code for: Enzyme
  • Family: ABC transporter superfamily. Molybdate importer family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdenum import ATP-binding protein ModC. Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
  • Length (amino acid): 352
  • Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363

    		• Similar resistance genes in 'BacMet Predicted database'
    modE
  • BacMet ID: BAC0608
  • Code for: Regulator
  • Family: ModE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Transcriptional regulator ModE. The ModE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. It controls tungstate and molybdate homeostasis in bacteria.
  • Length (amino acid): 262
  • Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363, Grunden et al. 1996; Pubmed- 8550508

    		• Similar resistance genes in 'BacMet Predicted database'
    perO
  • BacMet ID: BAC0612
  • Code for: Enzyme
  • Family: ArsB/NhaD permeases family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Rhodobacter capsulatus
  • Location: Chromosome
  • Compound: Molybdenum (Mo), Tungsten (W), Vanadium (V)
  • Description: PerO is involved in molybdate uptake. In addition to importing molybdate, PerO probably importssulfate, tungstate, and vanadate.
  • Length (amino acid): 595
  • Reference: Gisin et al. 2010; Pubmed- 20851900

    		• Similar resistance genes in 'BacMet Predicted database'
    tunR
  • BacMet ID: BAC0601
  • Code for: Regulator
  • Family: TunR family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Tungstate-responsive regulator, TunR. It controls tungstate and molybdate homeostasis in sulfate-reducing deltaproteobacteria. TunR functions as an activator of the modA, modBC, and tunR genes in the absence of tungstate and repressed by tungstate. Regulates the ModABC transport system in Desulfovibrio spp.
  • Length (amino acid): 403
  • Reference: Kazarov et al. 2013; Pubmed- 23913324

    		• Similar resistance genes in 'BacMet Predicted database'
    tupA
  • BacMet ID: BAC0605
  • Code for: Binding protein
  • Family: ABC superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Eubacterium acidaminophilum
  • Location: Chromosome
  • Compound: Tungsten (W)
  • Description: Extracellular tungstate binding protein.
  • Length (amino acid): 286
  • Reference: Makdessi et al. 2001; Pubmed- 11292832

    		• Similar resistance genes in 'BacMet Predicted database'
    tupB
  • BacMet ID: BAC0606
  • Code for: Enzyme
  • Family: ABC superfamily, binding-protein-dependent transport system permease family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Eubacterium acidaminophilum
  • Location: Chromosome
  • Compound: Tungsten (W)
  • Description: Permease component of tungstate ABC transporter. TupB is an inner membrane protein.
  • Length (amino acid): 228
  • Reference: Makdessi et al. 2001; Pubmed- 11292832

    		• Similar resistance genes in 'BacMet Predicted database'
    tupC
  • BacMet ID: BAC0607
  • Code for: Enzyme
  • Family: ABC superfamily, ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Eubacterium acidaminophilum
  • Location: Chromosome
  • Compound: Tungsten (W)
  • Description: ATPase component of tungstate ABC transporter.
  • Length (amino acid): 214
  • Reference: Makdessi et al. 2001; Pubmed- 11292832

    		• Similar resistance genes in 'BacMet Predicted database'
    wtpA
  • BacMet ID: BAC0602
  • Code for: Binding protein
  • Family: ABC superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pyrococcus furiosus
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdate/tungstate-binding protein WtpA. Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate, with a preference for tungstate.
  • Length (amino acid): 345
  • Reference: Bevers et al. 2006; Pubmed- 16952940

    		• Similar resistance genes in 'BacMet Predicted database'
    wtpB
  • BacMet ID: BAC0603
  • Code for: Enzyme
  • Family: ABC superfamily, binding-protein-dependent transport system permease family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pyrococcus furiosus
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdate/tungstate transport system permease protein WtpB. Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane.
  • Length (amino acid): 249
  • Reference: Bevers et al. 2006; Pubmed- 16952940

    		• Similar resistance genes in 'BacMet Predicted database'
    wtpC
  • BacMet ID: BAC0604
  • Code for: Enzyme
  • Family: ABC transporter superfamily. ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pyrococcus furiosus
  • Location: Chromosome
  • Compound: Tungsten (W), Molybdenum (Mo)
  • Description: Molybdate/tungstate import ATP-binding protein WtpC (ATPase). Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system.
  • Length (amino acid): 344
  • Reference: Bevers et al. 2006; Pubmed- 16952940

    		• Similar resistance genes in 'BacMet Predicted database'
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